ʻO ka Methyl acetate kahi ʻala ʻoluʻolu, hua a me ka ʻono ʻawaʻawa iki. Hiki ke hoʻomākaukau ʻia ma ka hoʻolapalapa ʻana i ka ʻakika acetic a me ka methanol i mua o nā mea hoʻokalakupua; a i ʻole ma ka hoʻomehana ʻana i ka methanol me kahi kalapona monoxide keu ma lalo o ke kaomi i mua o kahi catalyst (ʻakika phosphoric, nā paʻakai cobalt).
Hiki maoli ka Methyl acetate i nā haʻahaʻa haʻahaʻa i loko o ka mint, fungus, nā hua waina, ka maiʻa, ka kofe (Furia a me Bellanca, 1975) a he mea paʻakikī o nā nectarine (Takeoka et al., 1988). Aia kekahi i loko o kekahi mau mea inu ʻawaʻawa i hoʻoheheʻe ʻia (Shimoda et al., 1993). Hana ʻia ia ma ka ʻoihana ma o ka carbonylation o ka methanol ma ke ʻano he hopena o ka hana ʻana o ka ʻakika acetic a i ʻole ma ka esterification o ka acetic acid me ka methanol i mua o ka waikawa ikaika e like me ka sulfuric acid.